Hamster sera shown as open triangles. BA.1 reactivity increased by x2.4, JN.1 reactivity reduced by x0.2, Gamma reactivity reduced by x0.5.
Landscape titer (multi exposure) reactivities were adjusted by the same amount. Titers below the Limit of Detection (<LOD) titers were dealt with as LOD/2. The limit of detection for <LOD titers was adjusted by the same amount.
Landscape slopes quantify cross neutralization
## infection first infection second no event first
## 0.8698137 0.4278490 0.8970693
## no event second vaccine + inf first vaccine + inf second
## 0.8931188 0.9488968 0.5294982
## vaccine first vaccine second
## 0.8147309 0.6757184
Difference between fitted and measured data (calculated GMT).
RMSE (root mean squared error) between individual sample titers and individual landscape fits. Difference is given as a factor as it is the difference of log2 titers.